Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 10/20 | 0.36 |
| ▸ | IL2 | P60568 | 10/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007197 | 0.94 | CCR1 (0.33) | — | |
| SCHEMBL8004923 | 0.90 | PYGL (0.37) | CYP51A1 | |
| SCHEMBL8004714 | 0.89 | ALOX15 (0.40) | CYP51A1 | |
| SCHEMBL8006223 | 0.88 | PYGL (0.39) | CYP51A1 | |
| SCHEMBL7995046 | 0.88 | NPC1 (0.31) | — | |
| SCHEMBL4058202 | 0.87 | ALB (0.38) | ALBIL2DPP4CYP51A1TNF | |
| SCHEMBL7997127 | 0.86 | STAT6 (0.36) | CYP51A1 | |
| SCHEMBL7995568 | 0.84 | DRD2 (0.34) | CYP51A1 | |
| SCHEMBL7996360 | 0.81 | SMYD3 (0.36) | CYP51A1 | |
| SCHEMBL8007063 | 0.80 | TRPV4 (0.42) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111680-A1 | TRPV4 ANTAGONISTS | SMITHLINE BEECHAM CORPORATION (US) | 2009-09-11 | — | — | WO | disclosed |