Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 4/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12569981 | 0.87 | ALDH1A1 (0.32) | APOBEC3AAPOBEC3GPDE4AADORA2APDE4B | |
| SCHEMBL12824833 | 0.85 | PDE4A (0.35) | APOBEC3AAPOBEC3GPDE4AADORA2APDE4B | |
| SCHEMBL24662495 | 0.83 | APOBEC3A (0.33) | APOBEC3AAPOBEC3GPDE4AADORA2APDE4B | |
| SCHEMBL31332946 | 0.76 | GABRB3 (0.35) | APOBEC3AAPOBEC3GPDE4AADORA2APDE4B | |
| SCHEMBL8011007 | 0.74 | — | — | |
| SCHEMBL22125858 | 0.72 | — | — | |
| SCHEMBL859688 | 0.72 | — | — | |
| SCHEMBL17691218 | 0.70 | — | — | |
| SCHEMBL2397441 | 0.70 | — | — | |
| SCHEMBL31332821 | 0.69 | ADORA2B (0.32) | ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019200114-A1 | METHODS FOR PREPARING SUBSTITUTED DIHYDROINDENE-4-CARBOXAMIDE COMPOUNDS | ARBUTUS BIOPHARMA CORPORATION (CA) | 2019-10-17 | — | — | WO | disclosed |