Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 2/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187791 | 0.96 | POLQ (0.61) | POLQPTGS2AKR1B1TDP1KDM4E | |
| SCHEMBL29718585 | 0.96 | POLQ (0.61) | POLQPTGS2AKR1B1TDP1KDM4E | |
| Hydrochloric Acid SCHEMBL2529825 | 0.94 | POLQ (0.59) | POLQPTGS2AKR1B1TDP1KDM4E | |
| SCHEMBL265536 | 0.83 | POLQ (0.59) | POLQTDP1KDM4EATMNPSR1 | |
| SCHEMBL31173765 | 0.83 | POLQ (0.59) | POLQTDP1KDM4EATMNPSR1 | |
| SCHEMBL6864363 | 0.82 | POLQ (0.58) | POLQPTGS2TDP1KDM4EATM | |
| SCHEMBL9892644 | 0.82 | PTGS2 (0.52) | POLQPTGS2AKR1B1TDP1NPSR1 | |
| SCHEMBL18583700 | 0.82 | PTGS2 (0.49) | POLQPTGS2AKR1B1TDP1 | |
| SCHEMBL30120786 | 0.82 | PTGS2 (0.52) | POLQPTGS2AKR1B1TDP1KDM4E | |
| SCHEMBL29718842 | 0.82 | PTGS2 (0.49) | POLQPTGS2AKR1B1TDP1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166257-A | METAL COMPLEX OF AN OPTICALLY ACTIVE BIS(1-PHOSPHA-2,3-DIPHENYL-4,5-DIMETHYLNORBORNADIENE) | RHODIA CHIMIE (FR) | 2000-12-26 | — | — | US | disclosed |