Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 2/20 | 0.41 |
| ▸ | LDHB | P07195 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13607807 | 0.87 | CA12 (0.43) | PPARAPPARGPPARDCA12CA1 | |
| SCHEMBL28438040 | 0.75 | TPMT (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8678225 | 0.74 | PPARA (0.51) | PPARAPTPN1PTPN11CA12CA1 | |
| SCHEMBL7096047 | 0.74 | HMGCR (0.49) | PPARAPPARGPPARDPTPN1PTPN11 | |
| SCHEMBL5587554 | 0.73 | LDHA (0.50) | PPARAPPARGPPARDPTPN1PTPN11 | |
| SCHEMBL5588802 | 0.73 | LDHA (0.46) | PPARAPPARGPPARDPTPN1PTPN11 | |
| SCHEMBL9774171 | 0.73 | TPMT (0.55) | PTPN1CA12CA1CA2CA7 | |
| SCHEMBL9460582 | 0.73 | KDM4E (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27816468 | 0.72 | MEN1 (0.40) | PPARAPTPN1PTPN11LDHALDHB | |
| SCHEMBL17301627 | 0.72 | FASN (0.55) | PPARAPPARGPPARDLDHALDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057315-A | INHIBIT BACTERIAL SIGNAL TRANSDUCTION IN MAMMALS | WARNER-LAMBERTT COMPANY (US) | 2000-05-02 | — | — | US | disclosed |
| EP-0942912-A1 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1999-09-22 | — | — | EP | disclosed |
| WO-1998025932-A1 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1998-06-18 | — | — | WO | disclosed |