Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011712 | 0.75 | PPARA (0.42) | TPMTALOX5CA12CA1CA2 | |
| SCHEMBL30803073 | 0.74 | PTGS2 (0.55) | TPMTPTGS2CA12CA1CA2 | |
| SCHEMBL13607807 | 0.71 | CA12 (0.43) | TPMTPTGS2CA12CA1CA2 | |
| SCHEMBL4397386 | 0.69 | TPMT (0.58) | TPMTPTGS2CA12CA1CA2 | |
| SCHEMBL10724105 | 0.69 | ALOX5 (0.52) | PTGS2ALOX5HTTMAPTCYP3A4 | |
| SCHEMBL1590793 | 0.67 | TPMT (0.56) | TPMTPTGS2ALOX5CA12CA1 | |
| SCHEMBL27491445 | 0.65 | CYP3A4 (0.54) | TPMTCA12CA1CA2CA7 | |
| SCHEMBL18883605 | 0.65 | TAAR1 (0.67) | ALOX5CYP3A4TDP1TTRMAPK1 | |
| SCHEMBL9460582 | 0.64 | KDM4E (0.50) | TPMTPTGS2CA12CA1CA2 | |
| SCHEMBL7718116 | 0.64 | CA12 (0.59) | TPMTPTGS2ALOX5CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111448182-A | Aztreonam derivative and application thereof | 阿里萨制药有限公司 | 2020-07-24 | — | — | CN | disclosed |