Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 5/20 | 0.59 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.59 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14385493 | 1.00 | GRIK1 (0.59) | GRIK1GRIK2FOLH1FPR2ALDH1A1 | |
| SCHEMBL12231028 | 0.84 | GRIK1 (0.43) | GRIK1GRIK2FOLH1CYP19A1PPARG | |
| SCHEMBL9049408 | 0.83 | GRIK1 (0.63) | GRIK1GRIK2FPR2ALDH1A1CYP19A1 | |
| SCHEMBL9306152 | 0.83 | GRIK1 (0.63) | GRIK1GRIK2FPR2ALDH1A1CYP19A1 | |
| SCHEMBL5494285 | 0.83 | GRIK1 (0.63) | GRIK1GRIK2FPR2ALDH1A1CYP19A1 | |
| SCHEMBL9306159 | 0.83 | GRIK1 (0.63) | GRIK1GRIK2FPR2ALDH1A1CYP19A1 | |
| SCHEMBL5494288 | 0.83 | GRIK1 (0.63) | GRIK1GRIK2FPR2ALDH1A1CYP19A1 | |
| SCHEMBL14485864 | 0.81 | GRIK1 (0.53) | GRIK1GRIK2FOLH1FPR2ALDH1A1 | |
| SCHEMBL28401839 | 0.81 | F7 (0.50) | ALDH1A1CYP19A1PPARGMAPTFFAR1 | |
| SCHEMBL40728 | 0.81 | GRIK1 (0.58) | GRIK1GRIK2FOLH1TDP1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120068118-A1 | NANOCRYSTAL DOPED MATRIXES | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120068118-A1 | NANOCRYSTAL DOPED MATRIXES | STRA6, EPHA6, PIR | GRIK1 3775/4885GRIK2 2965/4885FOLH1 4010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.