Sugi Predict

Sugi Predict / Compounds / SCHEMBL801203

SCHEMBL801203

SCHEMBL801203

c1ccc(P(c2ccccc2)c2ccc(-n3c4ccc(P(c5ccccc5)c5ccccc5)cc4c4cc(P(c5ccccc5)c5ccccc5)ccc43)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 5/20 0.47
▸ L3MBTL1 Q9Y468 3/20 0.47
▸ ATM Q13315 1/20 0.47
▸ CYP3A4 P08684 2/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ ESR1 P03372 2/20 0.42
▸ ESR2 Q92731 2/20 0.42
▸ JAK2 O60674 1/20 0.34
▸ JAK3 P52333 1/20 0.34
▸ GAA P10253 2/20 0.33
▸ GFER P55789 1/20 0.33
▸ MEN1 O00255 3/20 0.33
▸ KMT2A Q03164 3/20 0.33
▸ HPGD P15428 3/20 0.33
▸ LMNA P02545 2/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ MAPK1 P28482 2/20 0.33
▸ HSD17B10 Q99714 2/20 0.33
▸ HTT P42858 2/20 0.33
▸ TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL782778 0.96 KDM4E (0.52) KDM4EL3MBTL1ATMCYP3A4TDP1
SCHEMBL801793 0.95 KDM4E (0.57) KDM4EL3MBTL1ATMCYP3A4TDP1
SCHEMBL801509 0.91 L3MBTL1 (0.62) KDM4EL3MBTL1ATMCYP3A4TDP1
SCHEMBL781505 0.91 L3MBTL1 (0.62) KDM4EL3MBTL1ATMCYP3A4TDP1
SCHEMBL28606169 0.89 KDM4E (0.38) KDM4EL3MBTL1ATMCYP3A4TDP1
SCHEMBL14948506 0.87 KDM4E (0.52) KDM4EL3MBTL1ATMCYP3A4TDP1
SCHEMBL14909983 0.84 KDM4E (0.53) KDM4EL3MBTL1ATMCYP3A4TDP1
SCHEMBL30775140 0.84 KDM4E (0.53) KDM4EL3MBTL1ATMCYP3A4TDP1
SCHEMBL14910075 0.84 KDM4E (0.53) KDM4EL3MBTL1ATMCYP3A4TDP1
SCHEMBL19362147 0.84 KDM4E (0.53) KDM4EL3MBTL1ATMCYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9278986-B2 Carbazole-based phosphine oxide compound, and organic electroluminescent device including the same SK CHEMICALS CO., LTD. (KR) 2016-03-08 — — US disclosed
US-9278986-B2 Carbazole-based phosphine oxide compound, and organic electroluminescent device including the same SK CHEMICALS CO., LTD. (KR) 2016-03-08 — — US disclosed
US-20120068168-A1 CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME INDUSTRY-ACADEMIC COOPERATION FOUNDATION, DANKOOK UNIVERSITY (KR) 2012-03-22 — — US disclosed
US-20120068168-A1 CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME INDUSTRY-ACADEMIC COOPERATION FOUNDATION, DANKOOK UNIVERSITY (KR) 2012-03-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120068168-A1 CARBAZOLE-BASED PHOSPHINE OXIDE COMPOUND, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME INPP5B, EZH2, PLCB3 KDM4E 1186/4885L3MBTL1 1822/4885ATM 3758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.