Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | STS | P08842 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6649609 | 0.89 | ALDH1A1 (0.48) | ALDH1A1STSMEN1KMT2AEPHX2 | |
| SCHEMBL6649701 | 0.86 | ALDH1A1 (0.43) | ALDH1A1STSMEN1KMT2AEPHX2 | |
| SCHEMBL6650959 | 0.86 | ALDH1A1 (0.43) | ALDH1A1STSMEN1KMT2AEPHX2 | |
| SCHEMBL8878468 | 0.86 | ALDH1A1 (0.43) | ALDH1A1STSMEN1KMT2AEPHX2 | |
| SCHEMBL8878473 | 0.86 | ALDH1A1 (0.43) | ALDH1A1STSMEN1KMT2AEPHX2 | |
| SCHEMBL19892893 | 0.84 | ALDH1A1 (0.44) | ALDH1A1STSMEN1KMT2AKDM1A | |
| SCHEMBL31064582 | 0.81 | GPR119 (0.43) | ALDH1A1STSMEN1KMT2AKDM1A | |
| SCHEMBL29457639 | 0.80 | KDM1A (0.55) | MEN1KMT2AKDM1AGPR119KDM4E | |
| SCHEMBL2174623 | 0.80 | KDM1A (0.55) | MEN1KMT2AKDM1AGPR119KDM4E | |
| SCHEMBL29457605 | 0.80 | KDM1A (0.55) | MEN1KMT2AKDM1AGPR119KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093821-A | MAKING 6-(PHENYL OR HETEROARYL)-1,2-DIHYDRO-N-1-PROTECTED QUINOLINE BY REACTING THE CORRESPONDING 6-HALO-DERIVATIVE WITH AN ORGANOBORATE AND ACID TREATMENT TO FORM THE 6-BORO-DERIVATIVE, COUPLING WITH PHENYL OR HETEROARYL HALIDE | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2000-07-25 | — | — | US | disclosed |