Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | STS | P08842 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GHSR | Q92847 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6650959 | 1.00 | ALDH1A1 (0.43) | ALDH1A1STSEPHX2MEN1KMT2A | |
| SCHEMBL8878473 | 1.00 | ALDH1A1 (0.43) | ALDH1A1STSEPHX2MEN1KMT2A | |
| SCHEMBL6649701 | 0.93 | ALDH1A1 (0.43) | ALDH1A1STSEPHX2MEN1KMT2A | |
| SCHEMBL8399608 | 0.86 | GPR119 (0.43) | EPHX2MEN1KMT2AKDM1AGPR119 | |
| SCHEMBL8013307 | 0.86 | ALDH1A1 (0.46) | ALDH1A1STSEPHX2MEN1KMT2A | |
| SCHEMBL6649609 | 0.85 | ALDH1A1 (0.48) | ALDH1A1STSEPHX2MEN1KMT2A | |
| SCHEMBL6653357 | 0.79 | GHSR (0.41) | ALDH1A1STSEPHX2MEN1KMT2A | |
| SCHEMBL14230676 | 0.74 | DRD2 (0.55) | ALDH1A1STSMEN1KMT2AGPR119 | |
| SCHEMBL30804525 | 0.74 | NOTUM (0.44) | ALDH1A1STSEPHX2MEN1KMT2A | |
| SCHEMBL6647243 | 0.74 | NOTUM (0.44) | ALDH1A1STSEPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693646-A | Steroid receptor modulator compounds and methods | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1997-12-02 | — | — | US | disclosed |