Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2908330 | 0.78 | EZH2 (0.89) | EZH2POLBKMT2AL3MBTL1MEN1 | |
| SCHEMBL8738163 | 0.75 | EZH2 (0.74) | EZH2POLBKMT2AL3MBTL1MEN1 | |
| SCHEMBL17067309 | 0.75 | POLB (0.59) | EZH2POLBKMT2AKDM4EHTT | |
| SCHEMBL7705146 | 0.74 | EZH2 (0.53) | EZH2POLBKMT2AKDM4EHTT | |
| SCHEMBL7699677 | 0.74 | EZH2 (0.60) | EZH2POLBKMT2AKDM4EHTT | |
| SCHEMBL7705142 | 0.74 | EZH2 (0.60) | EZH2POLBKMT2AKDM4EHTT | |
| SCHEMBL8738588 | 0.73 | EZH2 (1.00) | EZH2POLBKMT2AL3MBTL1MEN1 | |
| SCHEMBL310763 | 0.71 | KMT2A (0.82) | EZH2POLBKMT2AL3MBTL1MEN1 | |
| SCHEMBL6119822 | 0.70 | EZH2 (0.80) | EZH2POLBKMT2AL3MBTL1MEN1 | |
| SCHEMBL8504043 | 0.70 | KMT2A (0.76) | EZH2POLBKMT2AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975626-A1 | ENAMINE DERIVATIVES FOR USE AS ANTIOXYDANTS FOR POLYMERS | Great Lakes Chemical (Europe) GmbH (CH) | 2000-02-02 | — | — | EP | claimed |
| WO-1998047893-A1 | ENAMINE DERIVATIVES FOR USE AS ANTIOXYDANTS FOR POLYMERS | GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) | 1998-10-29 | — | — | WO | claimed |