Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11528562 | 0.87 | EZH2 (0.51) | EZH2POLBGAAHTTKMT2A | |
| SCHEMBL11530426 | 0.76 | EZH2 (0.47) | EZH2POLBGAAHTTKMT2A | |
| SCHEMBL2908330 | 0.74 | EZH2 (0.89) | EZH2POLBKMT2AL3MBTL1MEN1 | |
| SCHEMBL8013604 | 0.74 | EZH2 (0.57) | EZH2POLBGAAHTTKMT2A | |
| SCHEMBL15008597 | 0.72 | EZH2 (0.52) | EZH2POLBGAAHTTKMT2A | |
| SCHEMBL40016 | 0.71 | GAA (0.59) | EZH2POLBGAAHTTKMT2A | |
| SCHEMBL7705142 | 0.70 | EZH2 (0.60) | EZH2POLBGAAHTTKMT2A | |
| SCHEMBL7699677 | 0.70 | EZH2 (0.60) | EZH2POLBGAAHTTKMT2A | |
| SCHEMBL8738588 | 0.69 | EZH2 (1.00) | EZH2POLBKMT2AL3MBTL1MEN1 | |
| SCHEMBL11531594 | 0.68 | POLB (0.40) | EZH2POLBGAAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6353044-B1 | PHOTOSTABILITY OF POLYMER WITH BETA-(2,2,6,6-TETRAMETHYL PIPERIDINE-4-AMINO)ETHYL CROTONATE | GREAT LAKES CHEMICAL ITALIA S.R.L. (IT) | 2002-03-05 | — | — | US | disclosed |