Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NSD2 | O96028 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.51 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.51 |
| ▸ | PRKDC | P78527 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8010105 | 1.00 | KDM4E (0.61) | KDM4ETP53ARMAPTLMNA | |
| SCHEMBL39646 | 0.98 | KDM4E (0.63) | KDM4ETP53ARMAPTLMNA | |
| SCHEMBL6539258 | 0.96 | KDM4E (0.67) | KDM4ETP53ARMAPTLMNA | |
| SCHEMBL6065393 | 0.89 | KDM4E (0.80) | KDM4ETP53ARMAPTLMNA | |
| SCHEMBL12635872 | 0.88 | ALDH1A1 (0.65) | KDM4ETP53ARMAPTLMNA | |
| SCHEMBL18409046 | 0.88 | KDM4E (0.53) | KDM4ETP53ARMAPTLMNA | |
| SCHEMBL2384959 | 0.85 | KDM4E (0.80) | KDM4ETP53ALDH1A1CHRNA10CHRNA9 | |
| SCHEMBL7989190 | 0.81 | L3MBTL3 (0.54) | KDM4ETP53ARMEN1 | |
| SCHEMBL154178 | 0.81 | KDM4E (0.68) | KDM4ETP53MAPTLMNAHTT | |
| SCHEMBL7402909 | 0.81 | KDM4E (0.68) | KDM4ETP53MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143569-A | SUBSTITUTED BENZONITRILES WHICH EXHIBIT A SET OF THREE SEPARATE EMISSION BANDS IN RESPONSE TO LIGHT IN PRESENCE OF METAL IONS AND A SEPARATE SET OF THREE BANDS IN ABSENCE OF METAL IONS; INDICATOR FOR QUALITATIVE/QUANTITATIVE ANALYSIS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2000-11-07 | — | — | US | disclosed |