SCHEMBL8024783

SCHEMBL8024783

O=C1NC(=S)NC(=O)C1=C1CCCC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.45
MAPT P10636 3/20 0.45
ALDH1A1 P00352 3/20 0.45
POLB P06746 3/20 0.45
MEN1 O00255 2/20 0.45
BLM P54132 2/20 0.45
KMT2A Q03164 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
PLCG1 P19174 1/20 0.45
APEX1 P27695 1/20 0.45
APOBEC3A P31941 1/20 0.45
RECQL P46063 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
ESR2 Q92731 1/20 0.45
APOBEC3G Q9HC16 1/20 0.45
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
HSD17B10 Q99714 1/20 0.44
HTT P42858 2/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8014236 0.80 MAPT (0.41) HPGDMAPTALDH1A1POLBMEN1
SCHEMBL5483954 0.69
SCHEMBL12961171 0.62 ALDH1A1 (1.00) HPGDMAPTALDH1A1POLBMEN1
SCHEMBL12588783 0.60 POLB (0.40) HPGDMAPTALDH1A1POLBMEN1
SCHEMBL5807409 0.60 POLB (0.39) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL5807413 0.60 POLB (0.39) MAPTALDH1A1POLBMEN1BLM
SCHEMBL11937036 0.60 POLB (0.39) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL14964727 0.58 TDP2 (0.38) HPGDALDH1A1HSD17B10CRBN
SCHEMBL17714494 0.58 SIRT2 (0.48) ALDH1A1POLBMEN1KMT2ATDP1
SCHEMBL6616749 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6153356-A MIXTURE OF UNSATURATED COMPOUND, CYANINE DYE AND PHOTOINITIATOR MITSUBISHI CHEMICAL CORPORATION (JP) 2000-11-28 US disclosed