SCHEMBL8014256

SCHEMBL8014256

CCNc1ccc(C=O)c(Cc2cc(NCC)ccc2C=O)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.37
P2RX3 P56373 1/20 0.36
LMNA P02545 2/20 0.36
ALDH1A1 P00352 4/20 0.36
HPGD P15428 2/20 0.36
KDM4E B2RXH2 1/20 0.36
POLB P06746 1/20 0.36
CASP1 P29466 1/20 0.36
RECQL P46063 1/20 0.36
CASP7 P55210 1/20 0.36
HSD17B10 Q99714 1/20 0.36
ELANE P08246 1/20 0.34
AR P10275 2/20 0.33
PSEN1 P49768 1/20 0.33
PSEN2 P49810 1/20 0.33
APH1B Q8WW43 1/20 0.33
NCSTN Q92542 1/20 0.33
APH1A Q96BI3 1/20 0.33
PSENEN Q9NZ42 1/20 0.33
ADRA2A P08913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19674316 0.88 P2RX3 (0.34) MAPTP2RX3LMNAALDH1A1HPGD
SCHEMBL19674326 0.85 LMNA (0.37) MAPTP2RX3LMNAALDH1A1HPGD
SCHEMBL28385314 0.80 MAPT (0.38) MAPTP2RX3LMNAALDH1A1HPGD
SCHEMBL6554556 0.80 ALDH1A1 (0.41) MAPTLMNAALDH1A1HPGDKDM4E
SCHEMBL11333958 0.79 TYR (0.47) MAPTLMNAALDH1A1HPGDKDM4E
SCHEMBL19674218 0.78 ALDH1A1 (0.38) MAPTLMNAALDH1A1POLBAR
SCHEMBL12903822 0.76 ALDH1A1 (0.54) MAPTLMNAALDH1A1HPGDKDM4E
SCHEMBL27792205 0.75 ERN1 (0.47)
SCHEMBL24628669 0.74 ERN1 (0.40) MAPTALDH1A1KDM4E
SCHEMBL28172227 0.71 HTT (0.53) ALDH1A1HPGDL3MBTL1HTTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0847870-B1 Dyes for a thermal transfer dye-donor recording sheet DAINIPPON PRINTING CO LTD (JP) 2000-01-05 EP disclosed
EP-0847870-A1 Dyes for a thermal transfer dye-donor recording sheet DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1998-06-17 EP disclosed
EP-0727323-A1 Heat transfer sheet DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1996-08-21 EP disclosed
US-5304528-A With sublimable dye having two chromophores; high density, storage stability, colorfastness DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1994-04-19 US disclosed
EP-0582324-A1 Heat transfer sheet DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1994-02-09 EP disclosed
US-5223476-A HEAT TRANSFER SHEET DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1993-06-29 US disclosed
EP-0427867-A1 THERMAL TRANSFER SHEET DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1991-05-22 EP disclosed