SCHEMBL8014341

SCHEMBL8014341

O=S(=O)(F)c1cc(S(=O)(=O)F)cc(S(=O)(=O)Cl)c1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
F2 P00734 2/20 0.32
TMPRSS4 Q9NRS4 2/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218559 0.85 ALDH1A1 (0.53) ALDH1A1HSD17B10TDP1
SCHEMBL10570681 0.85 F2 (0.39) TDP1F2TMPRSS4TP53CYP1A2
SCHEMBL14030729 0.83 LCK (0.48) ALDH1A1HSD17B10TDP1F2TP53
SCHEMBL6514924 0.80 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1F2TMPRSS4
SCHEMBL6531618 0.78 ALDH1A1 (0.55) ALDH1A1HSD17B10TDP1F2TMPRSS4
SCHEMBL10575517 0.74 F2 (0.33) F2TMPRSS4TP53CYP1A2CYP2D6
SCHEMBL8014338 0.74 CA2 (0.48) ALDH1A1HSD17B10TDP1F2TMPRSS4
SCHEMBL18503855 0.72 HSD17B10 (0.42) ALDH1A1HSD17B10TDP1
SCHEMBL67496 0.72 ALDH1A1 (0.42) ALDH1A1HSD17B10TDP1
SCHEMBL18503851 0.72 BACE1 (0.37) TDP1F2TMPRSS4TP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6132943-A A MULTILAYER SILVER HALIDE COLOR PHOTOGRAPHIC FILM HAVING COLORED MASKING COUPLERS FOR CORRECTING THE UNWANTED YELLOW SIDE ABSORPTION OF MAGENTA DYE-FORMING COUPLERS EASTMAN KODAK COMPANY (US) 2000-10-17 US disclosed
US-6010839-A Color photographic elements containing yellow-colored magenta dye-forming masking couplers EASTMAN KODAK COMPANY (US) 2000-01-04 US disclosed