Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.32 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.32 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.32 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.32 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.32 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.32 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.32 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024790 | 0.86 | LMNA (0.38) | EGFRRPS6KB1AKT1 | |
| SCHEMBL8024896 | 0.86 | HDAC6 (0.41) | EGFRRPS6KB1 | |
| SCHEMBL8026454 | 0.85 | EGFR (0.42) | EGFRRPS6KB1AKT1ATP1A1ATP1B1 | |
| SCHEMBL8024728 | 0.85 | EGFR (0.49) | EGFRRPS6KB1ATP1A1ATP1B1ATP1A3 | |
| SCHEMBL8014117 | 0.85 | GALR3 (0.38) | EGFR | |
| SCHEMBL8025137 | 0.82 | EGFR (0.37) | EGFRRPS6KB1AKT1 | |
| SCHEMBL8014444 | 0.81 | SCN1A (0.36) | EGFRRPS6KB1AKT1 | |
| SCHEMBL8026446 | 0.81 | EGFR (0.35) | EGFRRPS6KB1AKT1ATP1A1ATP1B1 | |
| SCHEMBL8014557 | 0.77 | EGFR (0.37) | EGFRSLC6A4 | |
| SCHEMBL8026760 | 0.75 | CNR1 (0.35) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543402-B1 | Aralkylaminopyrimidine derivative, method for preparing the same and composition for controlling noxious organisms | UBE INDUSTRIES (JP) | 2000-03-01 | — | — | EP | claimed |
| US-5280025-A | Aralkylaminopyrimidine derivative, and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1994-01-18 | — | — | US | claimed |
| EP-0543402-A1 | Aralkylaminopyrimidine derivative, method for preparing the same and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1993-05-26 | — | — | EP | claimed |