Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 5/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 5/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | SCN1B | Q07699 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024904 | 0.88 | RORC (0.37) | EGFRKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL8024896 | 0.84 | HDAC6 (0.41) | RPS6KB1EGFRMEN1KMT2A | |
| SCHEMBL8024790 | 0.84 | LMNA (0.38) | RPS6KB1EGFRAKT1ALDH1A1 | |
| SCHEMBL8026454 | 0.83 | EGFR (0.42) | RPS6KB1EGFRAKT1 | |
| SCHEMBL8024728 | 0.83 | EGFR (0.49) | RPS6KB1EGFRKDM4E | |
| SCHEMBL8026446 | 0.82 | EGFR (0.35) | RPS6KB1EGFRAKT1 | |
| SCHEMBL8014465 | 0.81 | EGFR (0.36) | RPS6KB1EGFRAKT1 | |
| SCHEMBL8014577 | 0.81 | CNR1 (0.39) | EGFRKDM4EALDH1A1HPGD | |
| SCHEMBL8025137 | 0.81 | EGFR (0.37) | RPS6KB1EGFRAKT1MEN1KMT2A | |
| SCHEMBL8014530 | 0.79 | EGFR (0.34) | EGFRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543402-B1 | Aralkylaminopyrimidine derivative, method for preparing the same and composition for controlling noxious organisms | UBE INDUSTRIES (JP) | 2000-03-01 | — | — | EP | claimed |
| US-5280025-A | Aralkylaminopyrimidine derivative, and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1994-01-18 | — | — | US | claimed |
| EP-0543402-A1 | Aralkylaminopyrimidine derivative, method for preparing the same and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1993-05-26 | — | — | EP | claimed |