Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.38 |
| ▸ | EGFR | P00533 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024790 | 0.90 | LMNA (0.38) | RPS6KB1EGFRAURKA | |
| SCHEMBL8026454 | 0.89 | EGFR (0.42) | RPS6KB1EGFR | |
| SCHEMBL8024728 | 0.88 | EGFR (0.49) | RPS6KB1EGFR | |
| SCHEMBL8014465 | 0.86 | EGFR (0.36) | RPS6KB1EGFR | |
| SCHEMBL8025137 | 0.85 | EGFR (0.37) | HDAC6RPS6KB1EGFRMEN1KMT2A | |
| SCHEMBL8014444 | 0.84 | SCN1A (0.36) | RPS6KB1EGFRMEN1KMT2A | |
| SCHEMBL8026446 | 0.84 | EGFR (0.35) | RPS6KB1EGFR | |
| SCHEMBL9084666 | 0.77 | PTGER4 (0.40) | HDAC6RPS6KB1EGFRAURKA | |
| Hydrochloric Acid SCHEMBL9523871 | 0.76 | PTGER4 (0.39) | HDAC6RPS6KB1EGFRAURKA | |
| SCHEMBL8014470 | 0.73 | CXCR1 (0.33) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543402-B1 | Aralkylaminopyrimidine derivative, method for preparing the same and composition for controlling noxious organisms | UBE INDUSTRIES (JP) | 2000-03-01 | — | — | EP | claimed |
| US-5280025-A | Aralkylaminopyrimidine derivative, and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1994-01-18 | — | — | US | claimed |
| EP-0543402-A1 | Aralkylaminopyrimidine derivative, method for preparing the same and chemical for controlling noxious organisms containing the same | UBE INDUSTRIES, LTD. (JP) | 1993-05-26 | — | — | EP | claimed |