Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.43 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003306 | 0.77 | TSHR (0.55) | ALDH1A1TSHRHTTPOLBPKM | |
| SCHEMBL8405651 | 0.76 | ALDH1A1 (0.49) | ALDH1A1TSHRHTTPOLBPKM | |
| SCHEMBL8003307 | 0.76 | ALDH1A1 (0.51) | ALDH1A1TSHRHTTPOLBPKM | |
| SCHEMBL8012949 | 0.75 | BMP1 (0.52) | ALDH1A1TSHRHTTPOLBPKM | |
| SCHEMBL8012143 | 0.74 | MMP2 (0.54) | ALDH1A1TSHRHTTPOLBPKM | |
| SCHEMBL27562106 | 0.74 | CAMK2A (0.45) | ALDH1A1TSHRHTTPOLBSMN1; SMN2 | |
| SCHEMBL8400807 | 0.73 | ALDH1A1 (0.53) | ALDH1A1TSHRHTTPOLBPKM | |
| SCHEMBL8003278 | 0.73 | BMP1 (0.52) | ALDH1A1TSHRHTTPOLBPKM | |
| Water SCHEMBL27502519 | 0.73 | CAMK2A (0.45) | ALDH1A1TSHRHTTPOLBSMN1; SMN2 | |
| SCHEMBL8400820 | 0.73 | ALDH1A1 (0.49) | ALDH1A1TSHRHTTPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153609-A | Arylsulfonylamino hydroxamic acid derivatives | PFIZER INC (US) | 2000-11-28 | — | — | US | claimed |
| US-6153609-A | Arylsulfonylamino hydroxamic acid derivatives | PFIZER INC (US) | 2000-11-28 | — | — | US | disclosed |
| EP-0922030-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1999-06-16 | — | — | EP | disclosed |
| WO-1998007697-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1998-02-26 | — | — | WO | disclosed |