Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.61 |
| ▸ | RXRB | P28702 | 1/20 | 0.61 |
| ▸ | RXRG | P48443 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | RARG | P13631 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7331535 | 0.92 | RARB (0.63) | RXRARXRBRXRGKDM4ERARB | |
| SCHEMBL9723851 | 0.89 | RARB (0.63) | RXRARXRBRXRGKDM4ERARB | |
| SCHEMBL3977527 | 0.89 | RARB (0.63) | RXRARXRBRXRGKDM4ERARB | |
| SCHEMBL6266863 | 0.89 | RARB (0.63) | RXRARXRBRXRGKDM4ERARB | |
| SCHEMBL10871804 | 0.89 | RARB (0.63) | RXRARXRBRXRGKDM4ERARB | |
| SCHEMBL8986580 | 0.89 | RARB (0.63) | RXRARXRBRXRGKDM4ERARB | |
| SCHEMBL8769909 | 0.89 | RARB (0.63) | RXRARXRBRXRGKDM4ERARB | |
| SCHEMBL9799861 | 0.89 | RARB (0.63) | RXRARXRBRXRGKDM4ERARB | |
| Hydrochloric Acid SCHEMBL8419152 | 0.87 | RARB (0.62) | RXRARXRBRXRGKDM4ERARB | |
| SCHEMBL3550156 | 0.86 | RXRA (0.66) | RXRARXRBRXRGEGFRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107458-A | FUNGICIDE WHICH IS BETA-1,3-GLYCAN SYNTHASE INHIBITOR; FOR PROPHYLAXIS AND TREATMENT OF PNEUMOCYSTIS CARINII INFECTIONS LIKE PNEUMONIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-22 | — | — | US | disclosed |