Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 18/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL76940 | 0.82 | PARP1 (0.57) | PARP1ARALDH1A1CYP2C9HPGD | |
| SCHEMBL76810 | 0.80 | PARP1 (0.48) | PARP1 | |
| SCHEMBL13265573 | 0.77 | PARP1 (0.71) | PARP1ARCYP2C9 | |
| SCHEMBL5096925 | 0.74 | PARP1 (0.70) | PARP1 | |
| SCHEMBL13665692 | 0.71 | MEN1 (0.52) | AR | |
| SCHEMBL13776979 | 0.71 | PARP1 (0.65) | PARP1 | |
| SCHEMBL4435003 | 0.68 | PARP1 (0.67) | PARP1 | |
| SCHEMBL6852425 | 0.68 | ALDH1A1 (0.52) | ALDH1A1 | |
| SCHEMBL20546828 | 0.66 | MAOA (0.59) | ALDH1A1DAO | |
| SCHEMBL20546750 | 0.66 | MAOA (0.62) | ALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009093032-A1 | PHTHALAZINONE DERIVATIVES | ASTRAZENECA AB (SE) | 2009-07-30 | — | — | WO | disclosed |