SCHEMBL8015111

SCHEMBL8015111

CO[SiH]1CCC(CCc2ccc(-c3ccc(F)cc3)cc2)CC1

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.44
ABCB1 P08183 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
KCNH2 Q12809 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7771491 0.81 MAOB (0.47) MAOB
SCHEMBL8083840 0.81 MAOB (0.47) MAOB
SCHEMBL8083843 0.81 MAOB (0.47) MAOB
SCHEMBL8092153 0.79 MAOB (0.43) MAOB
SCHEMBL8092154 0.79 MAOB (0.43) MAOB
SCHEMBL7771574 0.76 MAOB (0.40) MAOB
SCHEMBL7771579 0.76 MAOB (0.40) MAOB
SCHEMBL3716138 0.76 MAOB (0.60) MAOB
SCHEMBL8977283 0.75 MAOB (0.50) MAOBKCNH2
SCHEMBL8018152 0.74 S1PR1 (0.36) MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0670322-B1 A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it SHINETSU CHEMICAL CO (JP) 2000-01-19 EP disclosed
US-5582764-A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-12-10 US disclosed
EP-0670322-A1 A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it Shin-Etsu Chemical Co., Ltd. (JP) 1995-09-06 EP disclosed