Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7826351 | 0.88 | KMT2A (0.44) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL19358702 | 0.85 | ALDH1A1 (0.45) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL4704967 | 0.83 | ALDH1A1 (0.46) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL8212933 | 0.82 | KMT2A (0.48) | KMT2AMEN1KDM4EALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL5741762 | 0.81 | ALDH1A1 (0.45) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL16115753 | 0.79 | MAPK1 (0.49) | KMT2AMEN1KDM4EALDH1A1TDP1 | |
| SCHEMBL7822677 | 0.79 | KDM4E (0.40) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL2423817 | 0.78 | KDM4E (0.47) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL5742547 | 0.78 | KDM4E (0.39) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL20477417 | 0.78 | SMN1; SMN2 (0.56) | KMT2AMEN1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6100264-A | 5H, 10H-imidazo [1,2-A] indeno [1,2-E] pyrazin-4-one derivatives, their preparation, their intermediates and medicaments containing them | RHONE-POULENC RORER, S.A. (FR) | 2000-08-08 | — | — | US | disclosed |
| US-5990108-A | USEFUL AS ANTAGONISTS OF THE ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID (AMPA) RECEPTOR, ALSO KNOWN AS THE QUISQUALATE RECEPTOR, AND AS ANTAGONISTS OF THE N-METHYL-D-ASPARTATE (NMDA) RECEPTOR | RHONE POULENC RORER S.A. (FR) | 1999-11-23 | — | — | US | disclosed |