Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043882 | 1.00 | TSHR (0.39) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8098796 | 0.96 | GRM2 (0.37) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8098792 | 0.96 | GRM2 (0.37) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8015349 | 0.93 | TSHR (0.36) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8015343 | 0.93 | TSHR (0.36) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8015344 | 0.93 | TSHR (0.36) | TSHRSLC6A4SLC6A3DRD2DRD4 | |
| SCHEMBL8083951 | 0.87 | JAK2 (0.33) | TSHRALOX5PPARGHDAC3HDAC1 | |
| SCHEMBL8083947 | 0.87 | JAK2 (0.33) | TSHRALOX5PPARGHDAC3HDAC1 | |
| SCHEMBL7762581 | 0.87 | FAAH (0.35) | TSHRSLC6A4SLC6A3ALOX5PPARG | |
| SCHEMBL7762577 | 0.87 | FAAH (0.35) | TSHRSLC6A4SLC6A3ALOX5PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657460-B1 | A silacyclohexane compound, a method of prepraring it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-5496501-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0657460-A1 | A silacyclohexane compound, a method of prepraring it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-06-14 | — | — | EP | disclosed |