Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 19/20 | 0.50 |
| ▸ | MMP13 | P45452 | 19/20 | 0.50 |
| ▸ | MMP9 | P14780 | 15/20 | 0.50 |
| ▸ | MMP8 | P22894 | 15/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | MMP16 | P51512 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003329 | 0.91 | MMP2 (0.53) | MMP2MMP13MMP9MMP8MMP1 | |
| SCHEMBL2859028 | 0.73 | MMP2 (0.75) | MMP2MMP13MMP9MMP8 | |
| SCHEMBL2859033 | 0.73 | MMP2 (0.75) | MMP2MMP13MMP9MMP8 | |
| SCHEMBL8554136 | 0.73 | SMN1; SMN2 (0.45) | MMP2MMP13MMP9MMP8MMP1 | |
| SCHEMBL2858553 | 0.72 | MMP2 (0.74) | MMP2MMP13MMP9MMP8 | |
| SCHEMBL2858557 | 0.72 | MMP2 (0.74) | MMP2MMP13MMP9MMP8 | |
| SCHEMBL2858142 | 0.72 | MMP2 (0.71) | MMP2MMP13MMP9MMP8 | |
| SCHEMBL2858144 | 0.72 | MMP2 (0.71) | MMP2MMP13MMP9MMP8 | |
| SCHEMBL2860307 | 0.72 | MMP2 (0.68) | MMP2MMP13MMP9MMP8 | |
| SCHEMBL2857363 | 0.72 | MMP2 (0.68) | MMP2MMP13MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153609-A | Arylsulfonylamino hydroxamic acid derivatives | PFIZER INC (US) | 2000-11-28 | — | — | US | claimed |
| US-6153609-A | Arylsulfonylamino hydroxamic acid derivatives | PFIZER INC (US) | 2000-11-28 | — | — | US | disclosed |