Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 18/20 | 0.53 |
| ▸ | MMP13 | P45452 | 18/20 | 0.53 |
| ▸ | MMP9 | P14780 | 14/20 | 0.53 |
| ▸ | MMP8 | P22894 | 14/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | MMP14 | P50281 | 1/20 | 0.53 |
| ▸ | MMP16 | P51512 | 1/20 | 0.53 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8015368 | 0.91 | MMP2 (0.50) | MMP2MMP13MMP9MMP8MMP1 | |
| SCHEMBL8554136 | 0.81 | SMN1; SMN2 (0.45) | MMP2MMP13MMP9MMP8MMP1 | |
| SCHEMBL7537813 | 0.74 | MMP9 (0.62) | MMP2MMP13MMP9MMP8MMP1 | |
| SCHEMBL7537818 | 0.74 | MMP9 (0.62) | MMP2MMP13MMP9MMP8MMP1 | |
| SCHEMBL8019163 | 0.74 | MMP9 (0.49) | MMP2MMP13MMP9MMP8MMP1 | |
| SCHEMBL3916339 | 0.74 | MMP2 (0.60) | MMP2MMP13MMP9MMP8MMP1 | |
| SCHEMBL3916340 | 0.74 | MMP2 (0.60) | MMP2MMP13MMP9MMP8MMP1 | |
| SCHEMBL6903460 | 0.73 | MMP1 (0.53) | MMP2MMP13MMP9MMP8MMP1 | |
| SCHEMBL8012508 | 0.73 | MMP2 (0.56) | MMP2MMP13MMP9MMP8MMP1 | |
| SCHEMBL3917445 | 0.73 | MMP2 (0.67) | MMP2MMP13MMP9MMP8MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153609-A | Arylsulfonylamino hydroxamic acid derivatives | PFIZER INC (US) | 2000-11-28 | — | — | US | claimed |
| EP-0922030-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1999-06-16 | — | — | EP | claimed |
| WO-1998007697-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1998-02-26 | — | — | WO | claimed |
| US-6153609-A | Arylsulfonylamino hydroxamic acid derivatives | PFIZER INC (US) | 2000-11-28 | — | — | US | disclosed |
| EP-0922030-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1999-06-16 | — | — | EP | disclosed |
| WO-1998007697-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1998-02-26 | — | — | WO | disclosed |