Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BMP1 | P13497 | 7/20 | 0.41 |
| ▸ | MMP3 | P08254 | 6/20 | 0.41 |
| ▸ | MMP1 | P03956 | 4/20 | 0.40 |
| ▸ | MMP8 | P22894 | 3/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | MMP7 | P09237 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP14 | P50281 | 2/20 | 0.39 |
| ▸ | MMP16 | P51512 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003329 | 0.81 | MMP2 (0.53) | MMP3MMP1MMP8MMP13MMP2 | |
| SCHEMBL8015368 | 0.73 | MMP2 (0.50) | MMP3MMP1MMP8MMP13MMP2 | |
| SCHEMBL1965951 | 0.72 | MMP1 (0.53) | SMN1; SMN2BMP1MMP3MMP1MMP8 | |
| SCHEMBL3913911 | 0.72 | MEP1B (0.59) | BMP1MMP3MMP1MMP8MMP13 | |
| SCHEMBL8401078 | 0.70 | BMP1 (0.47) | BMP1MMP3MMP1MMP8MMP13 | |
| SCHEMBL5243658 | 0.70 | MMP1 (0.56) | BMP1MMP3MMP1MMP8MMP13 | |
| SCHEMBL6809658 | 0.70 | MMP13 (0.50) | SMN1; SMN2MMP1MMP13MMP7MMP2 | |
| SCHEMBL8404841 | 0.68 | BMP1 (0.43) | BMP1MMP3MMP1MMP8MMP13 | |
| SCHEMBL6691684 | 0.67 | MMP1 (0.79) | SMN1; SMN2MMP3MMP1MMP8MMP13 | |
| SCHEMBL6813091 | 0.67 | MMP1 (0.76) | SMN1; SMN2MMP3MMP1MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922030-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1999-06-16 | — | — | EP | claimed |
| WO-1998007697-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1998-02-26 | — | — | WO | claimed |