SCHEMBL8015491

SCHEMBL8015491

CCOCOCOC(=O)CCl

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.37
GAA P10253 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
ALDH1A1 P00352 5/20 0.37
TSHR P16473 1/20 0.37
TRPA1 O75762 1/20 0.34
POLB P06746 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
THRB P10828 1/20 0.32
ALOX15 P16050 1/20 0.32
SOAT1 P35610 1/20 0.32
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8022252 0.95
SCHEMBL13294860 0.81 NAAA (0.41) MGAMGAASIMGAM2ALDH1A1
SCHEMBL59424 0.78
SCHEMBL5675734 0.77 ALDH1A1 (0.58) MGAMGAASIMGAM2ALDH1A1
SCHEMBL25596544 0.76 ALDH1A1 (0.56) MGAMGAASIMGAM2ALDH1A1
Ammonia Solution, Strong SCHEMBL27890351 0.75
SCHEMBL27524000 0.75
Ethane SCHEMBL28238087 0.75
SCHEMBL447535 0.75
SCHEMBL15316797 0.75 CYP1A2 (0.44) MGAMGAASIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6030746-A CHEMICALLY AMPLIFIED POSITIVE RESIST COMPRISES A ORGANIC SOLVENT, AN ALKALI SOLUBLE RESIN, A PHOTOACID GENERATOR AND A DISSOLUTION RATE REGULATOR SHIN-ETSU CHEMICAL CO., LTD. (JP) 2000-02-29 US disclosed