Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CAMK2A | Q9UQM7 | 3/20 | 0.48 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.47 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL8018794 | 0.99 | TSHR (0.49) | TSHRPOLBSMN1; SMN2CAMK2ACAMK2G | |
| SCHEMBL8003306 | 0.91 | TSHR (0.55) | TSHRPOLBSMN1; SMN2HTTGAA | |
| SCHEMBL27540154 | 0.90 | MMP3 (0.48) | TSHRPOLBSMN1; SMN2CAMK2ACAMK2G | |
| SCHEMBL8014840 | 0.83 | MMP3 (0.46) | TSHRPOLBSMN1; SMN2CAMK2ACAMK2G | |
| SCHEMBL8014852 | 0.77 | MMP3 (0.48) | CAMK2ACAMK2GMMP3MEP1BHTR2A | |
| SCHEMBL8008082 | 0.76 | PTGES (0.47) | CAMK2ACAMK2GMMP3MEP1BHTR2A | |
| SCHEMBL8016090 | 0.75 | BMP1 (0.49) | TSHRPOLBSMN1; SMN2CAMK2ACAMK2G | |
| Water SCHEMBL8018798 | 0.74 | BMP1 (0.49) | TSHRPOLBSMN1; SMN2CAMK2ACAMK2G | |
| SCHEMBL8015014 | 0.74 | BMP1 (0.54) | MMP3 | |
| SCHEMBL27562106 | 0.73 | CAMK2A (0.45) | TSHRPOLBSMN1; SMN2CAMK2ACAMK2G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922030-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1999-06-16 | — | — | EP | claimed |
| WO-1998007697-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1998-02-26 | — | — | WO | claimed |
| US-6153609-A | Arylsulfonylamino hydroxamic acid derivatives | PFIZER INC (US) | 2000-11-28 | — | — | US | disclosed |
| EP-0922030-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1999-06-16 | — | — | EP | disclosed |
| WO-1998007697-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1998-02-26 | — | — | WO | disclosed |