Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | ITK | Q08881 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8015782 | 0.81 | RORC (0.58) | HDAC6HDAC1RORCADORA2A | |
| SCHEMBL8016095 | 0.78 | F2 (0.48) | HDAC6HDAC1F2ITKBCHE | |
| SCHEMBL8029864 | 0.76 | ALDH1A1 (0.49) | HDAC6HDAC1RORCBCHECNR2 | |
| SCHEMBL8032010 | 0.75 | CNR2 (0.48) | HDAC6HDAC1RORCBCHECNR2 | |
| SCHEMBL8029791 | 0.75 | RORC (0.45) | HDAC6HDAC1F2RORCITK | |
| SCHEMBL8029861 | 0.75 | PPARG (0.49) | HDAC6HDAC1BCHECNR2 | |
| SCHEMBL8026465 | 0.74 | CNR2 (0.43) | HDAC6HDAC1F2RORCITK | |
| SCHEMBL8028885 | 0.73 | HDAC6 (0.46) | HDAC6HDAC1F2BCHECNR2 | |
| SCHEMBL8017278 | 0.72 | ITK (0.51) | ITKCNR2ACSL1 | |
| SCHEMBL8027001 | 0.71 | F2 (0.74) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060166-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-1999040072-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-08-12 | — | — | WO | disclosed |