SCHEMBL8016290

SCHEMBL8016290

CC(=O)Oc1ccc(-c2nc3ccccc3nc2-c2ccc(OC(C)=O)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.57
TDP1 Q9NUW8 3/20 0.57
KDM4E B2RXH2 3/20 0.57
ALDH1A1 P00352 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
NPSR1 Q6W5P4 1/20 0.57
ELANE P08246 1/20 0.51
HSD17B10 Q99714 1/20 0.50
MAPT P10636 4/20 0.49
KMT2A Q03164 3/20 0.49
GAA P10253 3/20 0.49
MEN1 O00255 2/20 0.49
HSP90AA1 P07900 1/20 0.49
TSHR P16473 2/20 0.48
ABCB11 O95342 1/20 0.48
ESR1 P03372 1/20 0.48
CYP3A4 P08684 1/20 0.48
ADRA2A P08913 1/20 0.48
CYP2C9 P11712 1/20 0.48
PDE4A P27815 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12111531 0.88 ALDH1A1 (0.54) LMNATDP1KDM4EALDH1A1L3MBTL1
SCHEMBL12111618 0.88 ALDH1A1 (0.54) LMNATDP1KDM4EALDH1A1L3MBTL1
SCHEMBL12111660 0.88 ALDH1A1 (0.54) LMNATDP1KDM4EALDH1A1L3MBTL1
SCHEMBL12111628 0.88 ALDH1A1 (0.54) LMNATDP1KDM4EALDH1A1L3MBTL1
SCHEMBL12111535 0.87 ALDH1A1 (0.48) LMNATDP1KDM4EALDH1A1L3MBTL1
SCHEMBL1902570 0.81 LMNA (0.47) LMNATDP1KDM4EALDH1A1L3MBTL1
SCHEMBL15056456 0.80 NPC1 (0.73) KDM4EALDH1A1L3MBTL1NPSR1HSD17B10
SCHEMBL9638586 0.79 ELANE (0.51) LMNATDP1ALDH1A1NPSR1ELANE
SCHEMBL12111619 0.78 ALDH1A1 (0.52) LMNATDP1KDM4EALDH1A1L3MBTL1
SCHEMBL12111534 0.78 ALDH1A1 (0.52) LMNATDP1KDM4EALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711803-B1 Method for preventing emission of fluorescence from polyalkylenenaphthalene-2,6-dicarboxylate TEIJIN LTD (JP) 2000-01-19 EP claimed
US-5651926-A SYNERGISTIC SUPPRESSION WITH CYCLIC IMINO ESTERS AND QUINOXALINES TEIJIN LIMITED (JP) 1997-07-29 US claimed
EP-0711803-A2 Method for preventing emission of fluorescence from polyalkylenenaphthalene-2,6-dicarboxylate TEIJIN LIMITED (JP) 1996-05-15 EP claimed
EP-0711803-B1 Method for preventing emission of fluorescence from polyalkylenenaphthalene-2,6-dicarboxylate TEIJIN LTD (JP) 2000-01-19 EP disclosed
US-5651926-A SYNERGISTIC SUPPRESSION WITH CYCLIC IMINO ESTERS AND QUINOXALINES TEIJIN LIMITED (JP) 1997-07-29 US disclosed
EP-0711803-A2 Method for preventing emission of fluorescence from polyalkylenenaphthalene-2,6-dicarboxylate TEIJIN LIMITED (JP) 1996-05-15 EP disclosed