Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.43 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942516 | 0.86 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| SCHEMBL7933531 | 0.85 | NR5A2 (0.59) | ALDH1A1CA2CYP2C9CYP2C19HIF1A | |
| SCHEMBL7940363 | 0.79 | NR5A2 (0.56) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| SCHEMBL7933901 | 0.79 | CA2 (0.48) | ALDH1A1CA2POLBNR5A2NR5A1 | |
| SCHEMBL8018921 | 0.78 | LMNA (0.49) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| SCHEMBL7944869 | 0.77 | CYP1A2 (0.45) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| SCHEMBL7198879 | 0.76 | SMN1; SMN2 (0.65) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| SCHEMBL8604816 | 0.75 | NR5A2 (0.54) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| SCHEMBL7933847 | 0.75 | HSPA5 (0.51) | ALDH1A1SMN1; SMN2CA2POLBTYR | |
| SCHEMBL7636127 | 0.74 | SMN1; SMN2 (0.63) | ALDH1A1SMN1; SMN2CA2POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6075159-A | USE AS A STABILIZER FOR AN ORGANIC MATERIAL SUCH AS THERMOPLASTIC RESINS, THERMOSETTING RESINS, NATURAL OR SYNTHETIC RUBBERS, MINERAL OILS, LUBRICATING OILS, ADHESIVES AND PAINTS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-06-13 | — | — | US | disclosed |
| US-5914361-A | IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-06-22 | — | — | US | disclosed |