SCHEMBL5850344

SCHEMBL5850344

S=P(Cl)(Oc1ccccc1C(Cl)Cl)Oc1ccccc1C(Cl)Cl

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8016123 0.82 GABRA1 (0.38) LMNATSHR
SCHEMBL5850355 0.81
SCHEMBL5850440 0.80 LMNA (0.37) LMNASMN1; SMN2TSHR
SCHEMBL8019074 0.77 TSHR (0.46) LMNATSHR
SCHEMBL29184305 0.73 SLC6A4 (0.39) TSHR
SCHEMBL5850443 0.73 LMNA (0.35) LMNASMN1; SMN2
SCHEMBL28169579 0.72 CA1 (0.57) TSHR
SCHEMBL5851928 0.71 MAPT (0.41) LMNASMN1; SMN2TSHR
SCHEMBL8016586 0.71 CA1 (0.56) LMNASMN1; SMN2TSHR
SCHEMBL5850843 0.71 HTR7 (0.36) LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7153901-B2 Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production ALBEMARLE CORPORATION (US) 2006-12-26 US disclosed
EP-1685176-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2006-08-02 EP disclosed
WO-2005052018-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2005-06-09 WO disclosed
US-20050113495-A1 Flame retardant, additive compositions, and flame retardant polyurethanes ALBEMARLE CORPORATION 2005-05-26 US disclosed