Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | USP7 | Q93009 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019722 | 0.84 | HIF1A (0.50) | HIF1AUSP7NPC1RAB9APKM | |
| SCHEMBL8924222 | 0.76 | MAPT (0.47) | NPC1RAB9AALDH1A1LMNAHTR2C | |
| SCHEMBL7696846 | 0.76 | HIF1A (0.40) | HIF1AUSP7NPC1RAB9ACA12 | |
| SCHEMBL23400045 | 0.71 | HIF1A (0.56) | HIF1ANPC1RAB9APKMHTT | |
| SCHEMBL8765117 | 0.71 | ALDH1A1 (0.64) | HIF1ANPC1RAB9AHTTALDH1A1 | |
| SCHEMBL19582587 | 0.71 | HIF1A (0.47) | HIF1ANPC1RAB9APKMALDH1A1 | |
| SCHEMBL1874877 | 0.69 | PDE4A (0.51) | HIF1ANPC1RAB9APKMCA9 | |
| SCHEMBL4809703 | 0.69 | MAOA (0.42) | NPC1RAB9APKMALDH1A1LMNA | |
| SCHEMBL31276354 | 0.69 | NPBWR1 (0.56) | HIF1ANPC1RAB9AHTTALDH1A1 | |
| SCHEMBL23398941 | 0.69 | HTT (0.54) | HIF1ANPC1RAB9APKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130228-A | Polycyclic compounds | UNIVERSITY OF STRATHCLYDE (GB) | 2000-10-10 | — | — | US | disclosed |