Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 13/20 | 0.47 |
| ▸ | THRA | P10827 | 9/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | VDR | P11473 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019665 | 1.00 | VCAM1 (0.48) | VCAM1THRBTHRAENPP2VDR | |
| SCHEMBL7662894 | 0.95 | VCAM1 (0.53) | VCAM1THRBTHRAENPP2VDR | |
| SCHEMBL7659049 | 0.95 | VCAM1 (0.53) | VCAM1THRBTHRAENPP2VDR | |
| SCHEMBL7658947 | 0.90 | VCAM1 (0.47) | VCAM1THRBTHRAENPP2VDR | |
| SCHEMBL7658934 | 0.90 | VCAM1 (0.47) | VCAM1THRBTHRAENPP2VDR | |
| SCHEMBL7659041 | 0.80 | ALDH1A1 (0.49) | VCAM1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7659054 | 0.80 | ALDH1A1 (0.49) | VCAM1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL8021340 | 0.80 | VCAM1 (0.55) | VCAM1THRBTHRAVDRMAPT | |
| SCHEMBL8019214 | 0.79 | MEN1 (0.43) | VCAM1MAPTHTTMEN1KMT2A | |
| SCHEMBL7659541 | 0.79 | MAPT (0.54) | MAPTHTTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000058277-A1 | ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | claimed |