Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.55 |
| ▸ | THRA | P10827 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 10/20 | 0.46 |
| ▸ | VDR | P11473 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662894 | 0.84 | VCAM1 (0.53) | VCAM1THRAMAPTMEN1KMT2A | |
| SCHEMBL7659049 | 0.84 | VCAM1 (0.53) | VCAM1THRAMAPTMEN1KMT2A | |
| SCHEMBL8008740 | 0.83 | ENPP2 (0.39) | MEN1KMT2AALDH1A1GAALMNA | |
| SCHEMBL8019501 | 0.82 | ADORA3 (0.56) | MEN1KMT2AALDH1A1NPC1LMNA | |
| SCHEMBL8019665 | 0.80 | VCAM1 (0.48) | VCAM1THRAMAPTMEN1KMT2A | |
| SCHEMBL8019666 | 0.80 | VCAM1 (0.48) | VCAM1THRAMAPTMEN1KMT2A | |
| SCHEMBL7658947 | 0.79 | VCAM1 (0.47) | VCAM1THRAMAPTMEN1KMT2A | |
| SCHEMBL7658934 | 0.79 | VCAM1 (0.47) | VCAM1THRAMAPTMEN1KMT2A | |
| SCHEMBL8022556 | 0.79 | VCAM1 (0.44) | VCAM1THRAMAPTMEN1KMT2A | |
| SCHEMBL8021833 | 0.76 | ADORA3 (0.43) | MAPTMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000058277-A1 | ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | claimed |
| WO-2000058277-A1 | ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | disclosed |