Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL59198 | 0.91 | KEAP1 (0.65) | AKR1B1KEAP1FFAR1PTGER1PTGER4 | |
| SCHEMBL29410826 | 0.86 | AKR1B1 (0.76) | AKR1B1TDP1ADRA1ABCAT2CXCL8 | |
| SCHEMBL30359 | 0.86 | AKR1B1 (0.76) | AKR1B1TDP1ADRA1ABCAT2CXCL8 | |
| SCHEMBL9787626 | 0.86 | L3MBTL1 (0.53) | AKR1B1KEAP1FFAR1PTGER1PTGER4 | |
| SCHEMBL10355521 | 0.84 | MAPT (0.61) | AKR1B1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL10355897 | 0.84 | MAPT (0.61) | AKR1B1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL10355465 | 0.84 | MAPT (0.61) | AKR1B1HDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL10355522 | 0.84 | MAPT (0.61) | AKR1B1HDAC3MAPK1ADRA1AHDAC4 | |
| Iodide SCHEMBL31305035 | 0.84 | AKR1B1 (0.73) | AKR1B1TDP1ADRA1ABCAT2CXCL8 | |
| Hydrochloric Acid SCHEMBL6767821 | 0.84 | AKR1B1 (0.73) | AKR1B1TDP1ADRA1ABCAT2CXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020253077-A1 | USE OF DICARBOXYLIC ACID COMPOUNDS FOR CONTROLLING PLANT DISEASES | CHINA AGRICULTURAL UNIVERSITY (CN) | 2020-12-24 | — | — | WO | disclosed |
| CN-100351325-C | Polyanhydrides, process for the preparation, use in antifouling paint and antifouling paint containing polyanhydrides | JOTUN AS (NO) | 2007-11-28 | — | — | CN | disclosed |
| CN-1780885-A | Polyanhydrides, method for the production thereof, use thereof in antifouling paints, and antifouling paints containing polyanhydrides | JOTUN AS (NO) | 2006-05-31 | — | — | CN | disclosed |
| CN-1063180-C | 5H, 10H-imidazo [1, 2 -a] indeno [1, 2 -e] pyrazin-4-one derivatives, preparation thereof, and drugs containing said derivatives | RHONE POULENC RORER SA (FR) | 2001-03-14 | — | — | CN | disclosed |
| US-6100264-A | 5H, 10H-imidazo [1,2-A] indeno [1,2-E] pyrazin-4-one derivatives, their preparation, their intermediates and medicaments containing them | RHONE-POULENC RORER, S.A. (FR) | 2000-08-08 | — | — | US | disclosed |
| US-6057454-A | USEFUL FOR TREATING OR PREVENTING ALL ISCHAEMIAS (SUCH AS FOCAL OR GLOBAL ISCHAEMIA) RESULTING FROM CEREBROVASCULAR DISORDERS | RHONE-POULENC RORER S.A. (FR) | 2000-05-02 | — | — | US | disclosed |
| US-5990108-A | USEFUL AS ANTAGONISTS OF THE ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID (AMPA) RECEPTOR, ALSO KNOWN AS THE QUISQUALATE RECEPTOR, AND AS ANTAGONISTS OF THE N-METHYL-D-ASPARTATE (NMDA) RECEPTOR | RHONE POULENC RORER S.A. (FR) | 1999-11-23 | — | — | US | disclosed |
| US-5902803-A | 5H,10H-imidazo 1,2-a!indeno 1,2-e!pyrazin-4-one derivatives, preparation thereof, and drugs containing said derivatives | RHONE-POULENC RORER S.A. (FR) | 1999-05-11 | — | — | US | disclosed |
| CN-1207102-A | 5h,10h-imidazo[1,2-alpha] indeno [1,2-3] pyrazine-4-one derivatives preparation thereof, intermediates thereof and drugs containing same | RHONE POULENC RORER SA (FR) | 1999-02-03 | — | — | CN | disclosed |
| CN-1180357-A | 5H, 10H-imidazo [1, 2-a ] indeno [1, 2-e ] pyrazin-4-one derivatives, preparation thereof and medicaments containing same | RHONE POULENC RORER SA (FR) | 1998-04-29 | — | — | CN | disclosed |
| US-4021408-A | DYES, PESTICIDES, STABILIZERS FOR POLYMERS | BASF AKTIENGESELLSCHAFT (DT) | 1977-05-03 | — | — | US | disclosed |