Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.39 |
| ▸ | ARG1 | P05089 | 1/20 | 0.39 |
| ▸ | ARG2 | P78540 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019721 | 1.00 | SIGMAR1 (0.43) | SIGMAR1S1PR1S1PR5OPRM1OPRK1 | |
| SCHEMBL7491471 | 0.85 | SIGMAR1 (0.47) | SIGMAR1OPRM1OPRK1SLC18A3OPRD1 | |
| SCHEMBL7491948 | 0.83 | SIGMAR1 (0.46) | SIGMAR1OPRM1OPRK1OPRD1FUCA1 | |
| SCHEMBL8022956 | 0.83 | SIGMAR1 (0.46) | SIGMAR1OPRM1OPRK1OPRD1FUCA1 | |
| SCHEMBL7491954 | 0.83 | SIGMAR1 (0.43) | SIGMAR1OPRM1OPRK1EBPSLC18A3 | |
| SCHEMBL7484788 | 0.80 | SIGMAR1 (0.47) | SIGMAR1OPRM1OPRK1SLC18A3OPRD1 | |
| SCHEMBL7480993 | 0.77 | SIGMAR1 (0.42) | SIGMAR1S1PR1S1PR5OPRM1OPRK1 | |
| SCHEMBL7565511 | 0.74 | SIGMAR1 (0.41) | SIGMAR1ALDH1A1 | |
| SCHEMBL7484214 | 0.72 | SIGMAR1 (0.42) | SIGMAR1OPRM1OPRK1OPRD1FUCA1 | |
| SCHEMBL11625384 | 0.68 | SIGMAR1 (0.39) | SIGMAR1OPRM1OPRK1EBPSLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153640-A | FOR TREATING DEPRESSION, PANIC ATTACKS, OBSESSIVE-COMPULSIVE DISORDERS, PHOBIAS, IMPULSIVE DISORDERS, DRUG ABUSE OR ANXIETY | ADIR ET COMPAGNIE (FR) | 2000-11-28 | — | — | US | disclosed |