2,4-Dihydroxybenzoic Acid

2,4-Dihydroxybenzoic Acid

SCHEMBL8019740

CC=CC=CCc1c(O)ccc(C(=O)O)c1O.O=C(O)c1ccc(O)cc1O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.50
CA1 P00915 5/20 0.50
CA2 P00918 5/20 0.50
CA7 P43166 5/20 0.50
CA9 Q16790 5/20 0.50
CA14 Q9ULX7 5/20 0.50
ALDH1A1 P00352 2/20 0.50
TSHR P16473 1/20 0.50
TYR P14679 2/20 0.44
CYP19A1 P11511 2/20 0.44
ALOX5 P09917 1/20 0.40
PTGS2 P35354 1/20 0.40
HSP90AB1 P08238 1/20 0.39
PDK2 Q15119 1/20 0.39
PDK4 Q16654 1/20 0.39
PTPN1 P18031 2/20 0.39
DHODH Q02127 1/20 0.39
SERPINE1 P05121 1/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7872617 0.91 SELL (0.44) ALDH1A1TYRCYP19A1PTGS2PTPN1
SCHEMBL7878890 0.80 SELL (0.44) CA12CA1CA2CA7CA9
SCHEMBL7878898 0.80 SELL (0.44) CA12CA1CA2CA7CA9
SCHEMBL7876091 0.77 CA12 (0.43) CA12CA1CA2CA7CA9
SCHEMBL7876093 0.77 CA12 (0.43) CA12CA1CA2CA7CA9
SCHEMBL9474910 0.74 HMGB1 (0.35) CA12CA1CA2CA7CA9
SCHEMBL9474914 0.74 HMGB1 (0.35) CA12CA1CA2CA7CA9
2,4-Dihydroxybenzoic Acid SCHEMBL8921001 0.72 ALDH1A1 (0.95) CA12CA1CA2CA7CA9
SCHEMBL7872614 0.72 CA12 (0.59) CA12CA1CA2CA7CA9
Paraben SCHEMBL8015210 0.72 CA2 (0.42) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000040544-A1 ALIPHATICALLY UNSATURATED HYDROXY BENZOATES AND PRESERVATIVE COMPOSITIONS THEREOF ISP INVESTMENTS INC. (US) 2000-07-13 WO disclosed