SCHEMBL7876091

SCHEMBL7876091

C/C=C/C=C/Cc1cc(O)ccc1C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.43
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
CA7 P43166 3/20 0.43
CA9 Q16790 3/20 0.43
CA14 Q9ULX7 3/20 0.43
ALDH1A1 P00352 3/20 0.43
TSHR P16473 1/20 0.43
ALOX5 P09917 1/20 0.40
PTGS2 P35354 1/20 0.40
LCK P06239 4/20 0.39
EGFR P00533 3/20 0.39
TDP1 Q9NUW8 3/20 0.38
MAPT P10636 2/20 0.38
RGS12 O14924 1/20 0.38
CAMKK2 Q96RR4 1/20 0.38
NOX4 Q9NPH5 1/20 0.38
PTPN1 P18031 3/20 0.37
PTPN11 Q06124 2/20 0.37
PTPN2 P17706 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7876093 1.00 CA12 (0.43) CA12CA1CA2CA7CA9
Paraben SCHEMBL8015210 0.93 CA2 (0.42) CA12CA1CA2CA7CA9
SCHEMBL10828138 0.89 ALDH1A1 (0.47) CA12CA1CA2CA7CA9
SCHEMBL8015206 0.81 NPC1 (0.40) CA12CA1CA2CA7CA9
SCHEMBL17912502 0.81 CA12 (0.46) CA12CA1CA2CA7CA9
Sorbic Acid SCHEMBL27480689 0.79 CA12 (0.41) CA12CA1CA2CA7CA9
SCHEMBL17912498 0.79 PTPN1 (0.46) CA12CA1CA2CA7CA9
2,4-Dihydroxybenzoic Acid SCHEMBL8019740 0.77 CA12 (0.50) CA12CA1CA2CA7CA9
SCHEMBL1908071 0.77 ALDH1A1 (0.52) CA12CA1CA2CA7CA9
SCHEMBL17912493 0.77 BID (0.44) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316500-B1 FOR USE IN FOOD, BEVERAGE, COSMETIC, AGRICHEMICAL AND TOPICALLY APPLIED PHARMACEUTICAL FORMULATION FOR PREVENTING MICROORGANISM OR FUNGUS GROWTH ISP INVESTMENTS INC. 2001-11-13 US disclosed
WO-2000040544-A1 ALIPHATICALLY UNSATURATED HYDROXY BENZOATES AND PRESERVATIVE COMPOSITIONS THEREOF ISP INVESTMENTS INC. (US) 2000-07-13 WO disclosed