Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 4/20 | 0.50 |
| ▸ | PPARA | Q07869 | 4/20 | 0.50 |
| ▸ | FAAH | O00519 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8033220 | 0.93 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1FAAHPKMMAPK1 | |
| SCHEMBL8020084 | 0.89 | FAAH (0.54) | SMN1; SMN2ALDH1A1FAAHMAPK1MEN1 | |
| SCHEMBL8035728 | 0.86 | HRH3 (0.50) | SMN1; SMN2ALDH1A1PPARAFAAHPKM | |
| SCHEMBL8031463 | 0.86 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1FAAHPKMMAPK1 | |
| SCHEMBL8029869 | 0.84 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1FAAHPKMMAPK1 | |
| SCHEMBL8029944 | 0.84 | SIGMAR1 (0.53) | SMN1; SMN2ALDH1A1FAAHPKMMAPK1 | |
| SCHEMBL8020109 | 0.84 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1FAAHPKMMAPK1 | |
| SCHEMBL8029589 | 0.83 | TSHR (0.61) | SMN1; SMN2ALDH1A1FAAHPKMMAPK1 | |
| SCHEMBL8035720 | 0.83 | FAAH (0.51) | SMN1; SMN2ALDH1A1PPARGPPARAFAAH | |
| Hydrochloric Acid SCHEMBL8887455 | 0.82 | TSHR (0.60) | SMN1; SMN2ALDH1A1FAAHPKMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702010-B1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-03-15 | — | — | EP | disclosed |
| US-5668138-A | AFFINITY FOR SIGMA RECEPTORS, CENTRAL NERVOUS SYSTEM DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-09-16 | — | — | US | disclosed |
| EP-0702010-A1 | Benzopyranderivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-03-20 | — | — | EP | disclosed |