Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2865478 | 0.81 | GABRA1 (0.43) | GABRA1GABRB2TSHRCYP1A2CYP3A4 | |
| SCHEMBL258651 | 0.79 | TSHR (0.39) | TSHRCYP3A4LMNASLC6A2HTR2B | |
| SCHEMBL2917292 | 0.79 | GABRA1 (0.50) | GABRA1GABRB2TSHRCYP1A2CYP3A4 | |
| SCHEMBL13122927 | 0.77 | GABRA1 (0.37) | GABRA1GABRB2TSHRCYP1A2CYP3A4 | |
| Bromide SCHEMBL29193695 | 0.77 | GABRA1 (0.48) | GABRA1GABRB2TSHRCYP1A2CYP3A4 | |
| SCHEMBL8013826 | 0.75 | GABRA1 (0.36) | GABRA1GABRB2TSHRCYP1A2CYP3A4 | |
| SCHEMBL14626445 | 0.75 | CYP2D6 (0.45) | GABRA1GABRB2TSHRCYP1A2CYP3A4 | |
| SCHEMBL8013854 | 0.75 | P2RX7 (0.38) | GABRA1GABRB2TSHRCYP1A2CYP3A4 | |
| SCHEMBL11501742 | 0.74 | GABRA1 (0.50) | GABRA1GABRB2TSHRCYP1A2CYP3A4 | |
| SCHEMBL5220290 | 0.72 | GABRA1 (0.37) | GABRA1GABRB2TSHRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6031066-A | POLYMERIZING ALPHA, BETA-UNSATURATED CARBOXYLIC ACID ESTER CONTAINING A TERTIARY AMINO GROUP AS A POLYMERIZABLE MONOMER IN THE PRESENCE OF A PHOSPHORUS COMPOUND | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2000-02-29 | — | — | US | disclosed |