SCHEMBL5220290

SCHEMBL5220290

CC(Cl)c1ccccc1S

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.37
GABRB2 P47870 2/20 0.37
TSHR P16473 3/20 0.33
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
LMNA P02545 2/20 0.33
GABRG2 P18507 2/20 0.33
GABRB3 P28472 2/20 0.33
FAAH O00519 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
HPGD P15428 1/20 0.33
GABRB1 P18505 1/20 0.33
PTGS1 P23219 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2C P28335 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
HTR2B P41595 1/20 0.33
GABRA2 P47869 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2865478 0.83 GABRA1 (0.43) GABRA1GABRB2TSHRCYP1A2CYP3A4
SCHEMBL29986709 0.78 GABRA1 (0.52) GABRA1GABRB2TSHRCYP1A2CYP3A4
SCHEMBL21380574 0.78 TSHR (0.35) TSHRCYP3A4LMNASLC6A2HTR2B
SCHEMBL191352 0.78 GABRA1 (0.52) GABRA1GABRB2TSHRCYP1A2CYP3A4
SCHEMBL3911670 0.78 TSHR (0.41) TSHRCYP1A2CYP3A4LMNASLC6A2
SCHEMBL11501742 0.76 GABRA1 (0.50) GABRA1GABRB2TSHRCYP1A2CYP3A4
SCHEMBL13242010 0.76 GABRA1 (0.39) GABRA1GABRB2TSHRCYP1A2CYP3A4
SCHEMBL7741493 0.76 GABRA1 (0.50) GABRA1GABRB2TSHRCYP1A2CYP3A4
SCHEMBL24044259 0.74 GABRA1 (0.37) GABRA1GABRB2TSHRCYP1A2CYP3A4
SCHEMBL13145152 0.74 ADRB2 (0.47) TSHRCYP1A2CYP3A4LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240390851-A1 PHOTOCATALYTIC AEROBIC OXIDATION OF YPERITE OR AN ANALOG THEREOF COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2024-11-28 US disclosed
EP-4426674-A1 PHOTOCATALYTIC AEROBIC OXIDATION OF YPERITE OR AN ANALOG THEREOF Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2024-09-11 EP disclosed
WO-2023079111-A1 PHOTOCATALYTIC AEROBIC OXIDATION OF YPERITE OR AN ANALOG THEREOF COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2023-05-11 WO disclosed
CN-108467617-B Reactive surface coatings with chemical decontamination and biocidal properties 美国消毒器公司 2020-08-21 CN disclosed
EP-1228367-B1 AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF ASUBIO PHARMA CO LTD (JP) 2007-09-26 EP disclosed
US-20060178401-A1 Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof DAIICHI ASUBIO PHARMA CO., LTD. 2006-08-10 US disclosed
US-7067533-B2 Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof DAIICHI ASUBIO PHARMA CO., LTD. (JP) 2006-06-27 US disclosed
US-20040040841-A1 Chemical sensors utilizing conducting polymer compositions CITY BANK 2004-03-04 US disclosed
US-20040009095-A1 Universal decontamination by detoxifying chemical and biological warfare agents using a peroxymonosulfate ion (HSO5), a peroxide oxidant to form free hydroxyl radicals and an activator dispersed in an absorbent or gel; no byproducts LYNNTECH, INC. 2004-01-15 US disclosed
US-20030139447-A1 Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof ASUBIO PHARMA CO., LTD. (JP) 2003-07-24 US disclosed
US-6569353-B1 For detoxifying chemical and biological warfare agents without any toxic by-products; gel of oxidizers, water and a sorbent material LYNNTECH, INC. 2003-05-27 US disclosed
EP-1228367-A2 AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF SUNTORY LIMITED (JP) 2002-08-07 EP disclosed
WO-2001079170-A2 AMINOPHENOXYACETAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION CONTAINING THEREOF SUNTORY LIMITED (JP) 2001-10-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240390851-A1 PHOTOCATALYTIC AEROBIC OXIDATION OF YPERITE OR AN ANALOG THEREOF CYB5R3, CBR3, NOX4 GABRA1 1826/4885GABRB2 1347/4885TSHR 473/4885
US-20030139447-A1 Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof SCN10A, CAMK2A, CAMK2B GABRA1 2051/4885GABRB2 685/4885TSHR 4435/4885
US-20060178401-A1 Aminophenoxyacetamide derivatives and pharmaceutical composition containing thereof NR0B1, NR0B2, NR4A1 GABRA1 1334/4885GABRB2 767/4885TSHR 1461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.