Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020132 | 0.86 | CYP2A6 (0.41) | MAPTTDP1CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL8020177 | 0.82 | CYP1A2 (0.35) | MAPTTDP1CYP1A2ALDH1A1RAB9A | |
| SCHEMBL8023619 | 0.81 | MAPT (0.36) | MAPTL3MBTL1TDP1CYP1A2ALDH1A1 | |
| SCHEMBL8624095 | 0.78 | MCL1 (0.35) | MAPTCYP1A2ALDH1A1HSD17B10MEN1 | |
| SCHEMBL29447338 | 0.77 | ALDH1A1 (0.39) | MAPTTDP1ALDH1A1HIF1AHSD17B10 | |
| SCHEMBL3955072 | 0.77 | ALDH1A1 (0.39) | MAPTTDP1ALDH1A1HIF1AHSD17B10 | |
| SCHEMBL8029658 | 0.76 | CYP1A2 (0.44) | MAPTTDP1CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL8029934 | 0.76 | CYP1A2 (0.34) | CYP1A2ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL29695262 | 0.76 | ALDH1A1 (0.38) | MAPTTDP1ALDH1A1HIF1AHSD17B10 | |
| SCHEMBL6419128 | 0.75 | CYP2A6 (0.38) | MAPTTDP1CYP1A2ALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695756-B1 | Process for the preparation of compounds of the phosphane series as well as their use | CELANESE CHEM EUROPE GMBH (DE) | 2000-03-15 | — | — | EP | disclosed |
| US-5728886-A | Compounds of the phosphine group, their preparation and their use | HOECHST AG (DE) | 1998-03-17 | — | — | US | disclosed |
| EP-0695756-A1 | Compounds of the phosphane series, process for their preparation as well as their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-02-07 | — | — | EP | disclosed |