Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | RRM1 | P23921 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776442 | 0.91 | ALOX5 (0.36) | CYP1A2TSHRALOX5RRM1S100A4 | |
| SCHEMBL8020132 | 0.86 | CYP2A6 (0.41) | CYP1A2CYP2A6TSHRMAPTALDH1A1 | |
| SCHEMBL8020163 | 0.82 | MAPT (0.42) | CYP1A2CYP2A6TSHRMAPTALDH1A1 | |
| SCHEMBL8023619 | 0.81 | MAPT (0.36) | CYP1A2CYP2A6TSHRRRM1MAPT | |
| SCHEMBL8624095 | 0.78 | MCL1 (0.35) | CYP1A2CYP2A6TSHRMAPTALDH1A1 | |
| SCHEMBL3955072 | 0.77 | ALDH1A1 (0.39) | CYP2A6TSHRMAPTALDH1A1TDP1 | |
| SCHEMBL29447338 | 0.77 | ALDH1A1 (0.39) | CYP2A6TSHRMAPTALDH1A1TDP1 | |
| SCHEMBL8029658 | 0.76 | CYP1A2 (0.44) | CYP1A2CYP2A6TSHRMAPTALDH1A1 | |
| SCHEMBL8029934 | 0.76 | CYP1A2 (0.34) | CYP1A2CYP2A6TSHRALDH1A1MEN1 | |
| SCHEMBL29695262 | 0.76 | ALDH1A1 (0.38) | CYP2A6TSHRMAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0695756-B1 | Process for the preparation of compounds of the phosphane series as well as their use | CELANESE CHEM EUROPE GMBH (DE) | 2000-03-15 | — | — | EP | disclosed |
| US-5728886-A | Compounds of the phosphine group, their preparation and their use | HOECHST AG (DE) | 1998-03-17 | — | — | US | disclosed |
| EP-0695756-A1 | Compounds of the phosphane series, process for their preparation as well as their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-02-07 | — | — | EP | disclosed |