Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020206 | 1.00 | HCRTR1 (0.51) | HCRTR1L3MBTL1GLAMEN1KMT2A | |
| SCHEMBL8022171 | 0.85 | SGMS2 (0.52) | L3MBTL1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8022176 | 0.85 | SGMS2 (0.52) | L3MBTL1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8024968 | 0.84 | STAT3 (0.50) | L3MBTL1GLAALDH1A1KCNK3KCNK9 | |
| SCHEMBL8024975 | 0.84 | STAT3 (0.50) | L3MBTL1GLAALDH1A1KCNK3KCNK9 | |
| SCHEMBL8761574 | 0.80 | CTNNB1 (0.54) | L3MBTL1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8761579 | 0.80 | CTNNB1 (0.54) | L3MBTL1MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL8622450 | 0.79 | HIF1A (0.52) | L3MBTL1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8622454 | 0.79 | HIF1A (0.52) | L3MBTL1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9462157 | 0.78 | HTT (0.46) | MEN1KMT2AALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675133-B1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO CO (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5614470-A | AGRICULTURAL ANTHELMINTIC, ACARICIDE, INSECTICIDE | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0675133-A1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1995-10-04 | — | — | EP | disclosed |