Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024968 | 1.00 | STAT3 (0.50) | STAT3CA12CA1CA2CA9 | |
| SCHEMBL8761574 | 0.85 | CTNNB1 (0.54) | RAB9AHTTALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL8761579 | 0.85 | CTNNB1 (0.54) | RAB9AHTTALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL8020206 | 0.84 | HCRTR1 (0.51) | RAB9AHTTHPGDALDH1A1GLA | |
| SCHEMBL8020209 | 0.84 | HCRTR1 (0.51) | RAB9AHTTHPGDALDH1A1GLA | |
| SCHEMBL28826963 | 0.84 | CTNNB1 (0.45) | RAB9AHTTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL28609967 | 0.83 | HTT (0.46) | NPC1RAB9AHTTHPGDALDH1A1 | |
| SCHEMBL9462157 | 0.83 | HTT (0.46) | NPC1RAB9AHTTHPGDALDH1A1 | |
| SCHEMBL8022171 | 0.82 | SGMS2 (0.52) | NPC1HTTALDH1A1L3MBTL1 | |
| SCHEMBL8022176 | 0.82 | SGMS2 (0.52) | NPC1HTTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0675133-B1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO CO (JP) | 2000-01-12 | — | — | EP | disclosed |
| US-5614470-A | AGRICULTURAL ANTHELMINTIC, ACARICIDE, INSECTICIDE | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0675133-A1 | 13-Substituted milbemycin derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1995-10-04 | — | — | EP | disclosed |