SCHEMBL8020282

SCHEMBL8020282

Nc1ccc(Oc2ccc(-c3ccc(Oc4ccc(N)cc4)cc3)cc2)cc1.Nc1cccc(Oc2ccc(-c3ccc(Oc4cccc(N)c4)cc3)cc2)c1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.73
SMN1; SMN2 Q16637 3/20 0.73
MAPT P10636 3/20 0.73
MEN1 O00255 2/20 0.73
KMT2A Q03164 2/20 0.73
MITF O75030 1/20 0.73
GAA P10253 1/20 0.73
GFER P55789 1/20 0.73
NLRP1 Q9C000 1/20 0.73
NOD2 Q9HC29 1/20 0.73
MAOB P27338 2/20 0.70
MAOA P21397 2/20 0.59
NPC1 O15118 1/20 0.58
RAB9A P51151 1/20 0.58
NLRP3 Q96P20 1/20 0.58
CYP3A4 P08684 2/20 0.56
TSHR P16473 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
POLB P06746 1/20 0.52
HSP90AA1 P07900 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL261579 1.00 ALDH1A1 (0.73) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL30393189 0.96 MAOB (0.76) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL29352381 0.96 MAOB (0.76) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL4060068 0.96 MAOB (0.76) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL28969425 0.96 MAOB (0.76) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL203512 0.96 MAOB (0.76) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
Benzidine SCHEMBL29101248 0.94 MAOB (0.81) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
Hydrochloric Acid SCHEMBL30042874 0.94 MAOB (0.73) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
Ammonia Solution, Strong SCHEMBL9154424 0.94 MAOB (0.73) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
Water SCHEMBL3664641 0.94 MAOB (0.73) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6074709-A POLYIMIDE OF 2,2'-BIS(3,4-DICARBOXYPHENYL)HEXAFLUORO-PROPANE, 9,9-BIS(3-METHYL-4-AMINOPHENYL)FLUORENE, AND AT LEAST ONE OF P-PHENYLENEDIAMINE AND 2,5-DIMETHYL-P-PHENYLENEDIAMINE. 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-06-13 US disclosed