SCHEMBL261579

SCHEMBL261579

Nc1ccc(Oc2ccc(-c3ccc(Oc4cccc(N)c4)cc3)cc2)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.73
SMN1; SMN2 Q16637 3/20 0.73
MAPT P10636 3/20 0.73
MEN1 O00255 2/20 0.73
KMT2A Q03164 2/20 0.73
MITF O75030 1/20 0.73
GAA P10253 1/20 0.73
GFER P55789 1/20 0.73
NLRP1 Q9C000 1/20 0.73
NOD2 Q9HC29 1/20 0.73
MAOB P27338 2/20 0.70
MAOA P21397 2/20 0.59
NPC1 O15118 1/20 0.58
RAB9A P51151 1/20 0.58
NLRP3 Q96P20 1/20 0.58
CYP3A4 P08684 2/20 0.56
TSHR P16473 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
POLB P06746 1/20 0.52
HSP90AA1 P07900 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8020282 1.00 ALDH1A1 (0.73) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL30393189 0.96 MAOB (0.76) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL29352381 0.96 MAOB (0.76) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL4060068 0.96 MAOB (0.76) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL28969425 0.96 MAOB (0.76) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL203512 0.96 MAOB (0.76) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
Benzidine SCHEMBL29101248 0.94 MAOB (0.81) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
Hydrochloric Acid SCHEMBL30042874 0.94 MAOB (0.73) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
Ammonia Solution, Strong SCHEMBL9154424 0.94 MAOB (0.73) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
Water SCHEMBL3664641 0.94 MAOB (0.73) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2280963-B1 METHOD OF PURIFYING DIANHYDRIDES, THE DIANHYDRIDES FORMED THEREBY, AND POLYETHERIMIDES FORMED THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-07-20 EP disclosed
EP-2097375-B1 METHOD FOR PURIFYING BISIMIDES SABIC INNOVATIVE PLASTICS IP (NL) 2013-04-24 EP disclosed
EP-2089348-B1 METHOD FOR MAKING POLYETHERIMIDES SABIC INNOVATIVE PLASTICS IP (NL) 2013-02-20 EP disclosed
US-8134016-B2 Method for purifying dianhydrides SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-03-13 US disclosed
US-8013173-B2 Method of purifying dianhydrides, the dianhydrides formed thereby, and polyetherimides formed therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-09-06 US disclosed
US-7981996-B2 reaction of a diamine such as ortho, meta or para-phenylenediamine with an anhydride like 3- or 4-chlorophthalic anhydride (3-ClPA) in the presence of a solvent (ortho dichlorobenzene) at a temperature above the normal boiling point of the solvent to produce bis/halophthalobisimide/; limited solubility SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-07-19 US disclosed
EP-2094691-B1 METHOD FOR PURIFYING DIANHYDRIDES SABIC INNOVATIVE PLASTICS IP (NL) 2011-05-25 EP disclosed
US-7635744-B2 Trifluorovinyloxy monomers and polymers GENERAL ELECTRIC COMPANY (US) 2009-12-22 US disclosed
US-20090247727-A1 Method of Purifying Dianhydrides, the Dianhydrides Formed Thereby, and Polyetherimides Formed Therefrom SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-10-01 US disclosed
EP-2097375-A1 METHOD FOR PURIFYING BISIMIDES Sabic Innovative Plastics IP B.V. (NL) 2009-09-09 EP disclosed
US-20070238856-A1 Trifluorovinyloxy monomers and polymers GENERAL ELECTRIC COMPANY 2007-10-11 US disclosed
US-20070112170-A1 Benzimidazole-containing sulfonated polyimides GENERAL ELECTRIC COMPANY 2007-05-17 US disclosed
US-20070073035-A1 Method for making polyetherimides GENERAL ELECTRIC COMPANY (US) 2007-03-29 US disclosed
US-20070073063-A1 Method for purifying bisimides GENERAL ELECTRIC COMPANY (US) 2007-03-29 US disclosed
US-20070073066-A1 Method for purifying dianhydrides GENERAL ELECTRIC COMPANY (US) 2007-03-29 US disclosed
US-20060293528-A1 Method of purifying dianhydrides GENERAL ELECTRIC COMPANY 2006-12-28 US disclosed
US-7147906-B2 Data storage medium comprising polyimides GENERAL ELECTRIC COMPANY (US) 2006-12-12 US disclosed
EP-1641861-A1 DATA STORAGE MEDIUM COMPRISING POLYIMIDES GENERAL ELECTRIC COMPANY (US) 2006-04-05 EP disclosed
WO-2005005515-A1 DATA STORAGE MEDIUM COMPRISING POLYIMIDES GENERAL ELECTRIC COMPANY (US) 2005-01-20 WO disclosed
US-20040265605-A1 Data storage medium comprising polyimides GENERAL ELECTRIC COMPANY 2004-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070073063-A1 Method for purifying bisimides FHIT, PBRM1, TNS4 ALDH1A1 4754/4885SMN1; SMN2 1842/4885MAPT 1418/4885
US-20060293528-A1 Method of purifying dianhydrides CA3, UROD, CA7 ALDH1A1 1546/4885SMN1; SMN2 3053/4885MAPT 1075/4885
US-20070073066-A1 Method for purifying dianhydrides AQP4, TRRAP, GYPA ALDH1A1 2726/4885SMN1; SMN2 2824/4885MAPT 4310/4885
US-20090247727-A1 Method of Purifying Dianhydrides, the Dianhydrides Formed Thereby, and Polyetherimides Formed Therefrom CA7, CA4, CA13 ALDH1A1 2086/4885SMN1; SMN2 4507/4885MAPT 1729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.