Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 5/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | C5 | P01031 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8030661 | 0.95 | MTOR (0.36) | CASRPTGS2RORCMTORCXCR1 | |
| SCHEMBL8030433 | 0.94 | PTGS2 (0.35) | CASRPTGS2RORCMTORCXCR1 | |
| SCHEMBL8036248 | 0.93 | KMT2A (0.37) | CASRPTGS2RORCCXCR1CXCR2 | |
| SCHEMBL8020824 | 0.92 | CASR (0.35) | CASRRORC | |
| SCHEMBL8020101 | 0.91 | PTGS2 (0.36) | CASRPTGS2RORCMTORPTGS1 | |
| SCHEMBL8030599 | 0.91 | PTGS2 (0.36) | CASRPTGS2RORCMTORPTGS1 | |
| SCHEMBL8030140 | 0.90 | CASR (0.34) | CASRMTORCXCR1CXCR2OPRM1 | |
| SCHEMBL8034072 | 0.90 | BDKRB2 (0.40) | CASRCXCR1CXCR2 | |
| SCHEMBL8030348 | 0.90 | CASR (0.37) | CASRPTGS2RORCMTORMEN1 | |
| SCHEMBL27489407 | 0.89 | CASR (0.33) | CASRMTORCXCR1CXCR2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985660-A1 | AMINOPHENOL DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |